ASSESSMENT OF CYTOTOXICITY OF A CAFFEINATED SOFT DRINK USING ALLIUM ASSAY

One of the most consumed caffeinated soft drinks by millions people globally is Coca-Cola. For healthy adults, caffeine consumption relatively safe, but for some vulnerable populations, could be harmful. Therefore, we considered this cytogenetic study to appropriate assessment cytotoxicity effects Coca-Cola in meristematic cells plants, through Allium test. A. cepa has assayed one best model plants standard use cytological analysis different toxins their and genotoxicity animals. The roots were treated with various concentrations (3, 5 10ml/cl) 8 hours, at room temperature, along an untreated control. It was found that induced a strong cytogenotoxic effect as concentration increased. clastogenic aneugenic tested product manifested decrease mitotic index (12.5-3.5%) occurrence several types chromosomal nuclear abnormalities (12.6-23.2%): bridges, laggards, stickiness disrupted nucleus. These results suggest can harmful health regular intake must avoided. problem arises when regularized everyday life, as, unfortunately, many do.